| Unidirectional transfer of D-xylose across the rat placenta. | |
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MedLine Citation:
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PMID: 9493560 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The transplacental transfer of D-xylose was investigated in the present study. 2. Umbilical perfusion of the rat term placenta was used to study materno-foetal (M-F) and foetomaternal (F-M) transfer of this compound. 3. D-Xylose was found to cross the rat term placenta very quickly in the M-F direction, with subsequent accumulation in the foetal compartment (the F-M ratio being 2.23 at the end of the experiments). In contrast, no transfer in the F-M direction was observed. 4. A possible facilitation of the transplacental transfer of D-xylose from the mother to foetus in rats is suggested. |
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Authors:
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F Staud; Z Fendrich; R Karlícek; P Pávek |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical and experimental pharmacology & physiology Volume: 25 ISSN: 0305-1870 ISO Abbreviation: Clin. Exp. Pharmacol. Physiol. Publication Date: 1998 Jan |
Date Detail:
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Created Date: 1998-05-04 Completed Date: 1998-05-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0425076 Medline TA: Clin Exp Pharmacol Physiol Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 54-6 Citation Subset: IM |
Affiliation:
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Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovského, Czech Republic. fstaud@pharm.kyoto-u.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Transport, Active / physiology Female Maternal-Fetal Exchange / physiology* Perfusion Placenta / metabolism* Pregnancy Rats Rats, Wistar Time Factors Xylose / pharmacokinetics* |
| Chemical | |
Reg. No./Substance:
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0/Xylose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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