| Unicentric mixed variant Castleman disease associated with Hashimoto disease: the role of PET/CT in staging and evaluating response to the treatment. | |
| | |
MedLine Citation:
|
PMID: 21684830 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Castleman disease (CD) is a rare atypical lymphoproliferative disease, pathologically classified as hyaline vascular, plasma cell type and mixed type variant. The underlying cause of CD is unknown, however several theories including autoimmunity have been proposed. We describe a patient diagnosed with unicentric mixed variant CD and Hashimoto thyroiditis, concurrently. She was staged with fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) and the disease was localized to the mediastinum. After 6 cycles of chemotherapy consisting of vincristine and prednisone, the mediastinal lymph nodes regressed, but did not disappear from the CT scan. However, FDG-PET/CT showed complete metabolic response. Although the role of FDG-PET/CT in staging and evaluation of treatment response is controversial, this case shows that PET/CT can be effective and even better for staging and response evaluation. This case is also unique as there no case of CD in association with Hashimoto thyroiditis has been reported previously. However, the possibility of a coincidental association must be raised, especially when the high prevalence of Hashimoto thyroiditis is considered. |
| | |
Authors:
|
Cengiz Akosman; Nalan Alan Selcuk; Cetin Ordu; Sina Ercan; Isin Dogan Ekici; Basak Oyana |
Publication Detail:
|
Type: Journal Article Date: 2011-06-15 |
Journal Detail:
|
Title: Cancer imaging : the official publication of the International Cancer Imaging Society Volume: 11 ISSN: 1470-7330 ISO Abbreviation: Cancer Imaging Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-06-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101172931 Medline TA: Cancer Imaging Country: England |
Other Details:
|
Languages: eng Pagination: 52-5 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, Section of Medical Oncology. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quantitative (177)Lu SPECT (QSPECT) imaging using a commercially available SPECT/CT system.
Next Document: Arsenic Toxicology: Translating between Experimental Models and Human Pathology.