| Unfavourable outcomes of drug therapy--subjective probability versus confidence intervals. | |
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MedLine Citation:
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PMID: 3274044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate how individual predictions compare with confidence intervals, we asked 50 medical residents and 28 graduate students with biostatistics training to estimate unfavourable outcomes of drug therapy (therapeutic failures and side-effects) in groups of 10 and 20 patients. The predictions made by physicians and graduate students were similar for both sample sizes and types of outcome. The majority (58%) of estimates were greater than the upper limit of the 95% confidence interval, a bias that may hamper the correct interpretation of therapeutic risks in medical decision-making. |
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Authors:
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P Manu; T A Louis; T J Lane; L Gottlieb; P Engel; R M Rippey |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pharmacy and therapeutics Volume: 13 ISSN: 0269-4727 ISO Abbreviation: J Clin Pharm Ther Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1989-02-17 Completed Date: 1989-02-17 Revised Date: 2008-05-28 |
Medline Journal Info:
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Nlm Unique ID: 8704308 Medline TA: J Clin Pharm Ther Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 213-7 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Connecticut Health Center, Farmington. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biometry* Data Collection Decision Making Drug Therapy* / adverse effects* Education, Graduate Female Humans Internship and Residency Male Probability* Students, Health Occupations |
| Comments/Corrections | |
Comment In:
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J Clin Pharm Ther. 1989 Dec;14(6):481-2
[PMID:
2613774
]
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Erratum In:
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J Clin Pharm Ther 1989 Dec;14(6):482 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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