| Unexplained lymphadenopathy in homosexual men. A longitudinal study. | |
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MedLine Citation:
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PMID: 2991618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In January 1982, the Centers for Disease Control began a prospective study of unexplained generalized lymphadenopathy syndrome in 78 homosexual or bisexual men. As of Aug 1, 1984, the median durations of lymphadenopathy and enrollment were 29.5 months and 20 months, respectively. Antibodies to human T-cell lymphotropic virus type III/lymphadenopathy-associated virus were present in 75 (96%) of the study patients. Five (6%) of the patients were diagnosed as having the acquired immunodeficiency syndrome five to 25 months after the onset of lymphadenopathy. At the time of their initial visit, these five patients had lower T-helper cell counts, hematocrits, lymphocyte counts, and pokeweed mitogen stimulation ratios and were more likely to report severe symptoms than patients who did not develop the acquired immunodeficiency syndrome. During 318 follow-up visits, except for the development of the acquired immunodeficiency syndrome in five patients, there has been little change in the initial laboratory and clinical measures of this cohort. Within the follow-up period of this study, the features of lymphadenopathy syndrome have been unremitting for the majority of patients. |
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Authors:
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D B Fishbein; J E Kaplan; T J Spira; B Miller; L B Schonberger; P F Pinsky; J P Getchell; V S Kalyanaraman; J S Braude |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JAMA : the journal of the American Medical Association Volume: 254 ISSN: 0098-7484 ISO Abbreviation: JAMA Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1985-08-30 Completed Date: 1985-08-30 Revised Date: 2006-11-07 |
Medline Journal Info:
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Nlm Unique ID: 7501160 Medline TA: JAMA Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 930-5 Citation Subset: AIM; IM; X |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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blood,
epidemiology,
immunology Adult Antibodies, Viral / analysis Blood Cell Count Deltaretrovirus / immunology Enzyme-Linked Immunosorbent Assay Georgia Homosexuality* Humans Lymphatic Diseases / blood, epidemiology*, immunology, physiopathology Lymphocyte Activation Male Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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