| Unexplained dyspnea in an old patient with recurrent stroke: platypnea-orthodeoxia syndrome and evidence of patent foramen ovale. | |
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MedLine Citation:
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PMID: 19876592 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Platypnea-orthodeoxia is a syndrome characterized by dyspnea and hypoxemia in orthostatism relieved by supine position. This phenomenon is frequently associated with interatrial communication, mainly patent foramen ovale. The association of platypnea-orthodeoxia syndrome with recurrent stroke and patent foramen ovale is extremely uncommon. A 73-year-old woman experienced recurrent attacks of dyspnea after an ischemic stroke. Arterial blood gas analysis changes in upright and supine position confirmed the diagnosis of platypnea-orthodeoxia syndrome. Contrast-enhanced transthoracic echocardiography showed patent foramen ovale with atrial septal aneurysm and right-to-left shunt. Percutaneous closure of patent foramen ovale led to stabilization of blood oxygen saturation and resolution of dyspnea. Platypnea-orthodeoxia syndrome should be considered in patients with stroke and unexplained dyspnea. The diagnosis could lead to correction of an unknown cardiac defect and of potential risk factor for stroke. |
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Authors:
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Monica Angelini; Giorgio Lambru; Sara Montepietra; Massimo Riccardi; Carla Zanferrari; Ermelinda Bortone |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-10-30 |
Journal Detail:
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Title: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Volume: 31 ISSN: 1590-3478 ISO Abbreviation: Neurol. Sci. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-26 Completed Date: 2010-04-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959175 Medline TA: Neurol Sci Country: Italy |
Other Details:
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Languages: eng Pagination: 93-4 Citation Subset: IM |
Affiliation:
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Neurology Section, Department of Neurosciences, University of Parma, Via Gramsci 14, 43100, Parma, Italy. monicaterina@yahoo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Gas Analysis Brain Ischemia / diagnosis*, physiopathology Diagnosis, Differential Dyspnea / diagnosis*, physiopathology Echocardiography Female Follow-Up Studies Foramen Ovale, Patent / diagnosis*, physiopathology, surgery Humans Oxygen / blood Recurrence Stroke / diagnosis*, physiopathology Syndrome Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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