Document Detail


Unenhanced MR angiography of the thoracic aorta: initial clinical evaluation.
MedLine Citation:
PMID:  18356435     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In patients with difficult i.v. access or renal insufficiency, or in those who are pregnant, we hypothesized than an unenhanced 3D segmented steady-state free precession (SSFP) MR angiography (MRA) technique would be an alternative to contrast-enhanced MR angiography (CE-MRA) for the evaluation of vasculature. MATERIALS AND METHODS: MRA examinations of the thoracic aorta were retrospectively reviewed in 23 patients in whom both CE-MRA and 3D SSFP were performed. CE-MRA was performed using an ECG-gated gradient-echo FLASH sequence. Three-dimensional SSFP MRA was performed during free breathing using a motion-adaptive navigator technique. Quantitative assessment of the 3D SSFP and CE-MRA image sets was performed by comparing the aortic lumen diameter. The quality of the images of the aortic root (scale of 1-5) and the presence of cardiovascular and noncardiovascular pathology were independently determined for both techniques by two reviewers. Bland-Altman and Wilcoxon's signed-rank analyses were performed. RESULTS: The difference in orthogonal measurements of the aortic diameter between those made on images from the 3D SSFP and those made from the CE-MRA sequences was -0.042 cm. The aortic root was better visualized with 3D SSFP: score of 3.78 (of 5) for CE-MRA versus score of 4.65 (of 5) for 3D SSFP (p < 0.05). CONCLUSION: In patients in whom contrast material is contraindicated, unenhanced MRA using a 3D SSFP technique can be performed.
Authors:
Christopher J François; David Tuite; Vibhas Deshpande; Renate Jerecic; Peter Weale; James C Carr
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  190     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-21     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  902-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Northwestern University, Chicago, IL, USA. cfrancois@uwhealth.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Aorta, Thoracic*
Aortic Diseases / diagnosis*
Electrocardiography
Female
Humans
Image Interpretation, Computer-Assisted
Imaging, Three-Dimensional
Magnetic Resonance Angiography / methods*
Male
Middle Aged
Retrospective Studies
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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