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Undifferentiated embryonal sarcoma of the liver in an adult patient: Case report.
MedLine Citation:
PMID:  22798120     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Undifferentiated embryonal sarcoma of the liver is a rare and aggressive tumor in adults, with an unfavorable prognosis. We present a 33-year-old female patient who was admitted with fatigue, weight loss and right upper abdominal pain. Magnetic resonance imaging of the liver revealed a bulky malignant mass with necrotic and cystic center, which nearly occupied the left lobe and invaded the middle-left hepatic vein and left portal vein. The patient was evaluated as inoperable, and in order to determine the histologic diagnosis, a Tru-cut biopsy was performed. Both histopathologic features and the immunocytochemical stainings revealed the diagnosis of hepatic embryonal sarcoma. Since the patient had no chance of surgery due to the advanced stage of the tumor and progressive hepatic failure, a combination chemotherapy was applied. Unfortunately, the patient did not respond to treatment at all and died in the second post-therapy week. Undifferentiated embryonal sarcoma of the liver is a highly chemo-sensitive tumor. Radical resection may be possible after combination chemotherapy in the childhood period, but since the disease is extremely rare in adults, an optimal treatment approach is still unknown.
Authors:
Umut Varol; Bur 231 Ak Karaca; U 287 Ur Muslu; Latife DO 286 Anay; Mustafa DE 286 304 Rmenc 304; R 252 231 Han Uslu; Erdem G Ouml Ker
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology     Volume:  23     ISSN:  1300-4948     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-7-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515841     Medline TA:  Turk J Gastroenterol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  279-283     Citation Subset:  -    
Affiliation:
Ege University Faculty of Medicine, Department of Medical Oncology, İzmir, Turkey. varolumut@yahoo.com.
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