| Understanding why contrast enhancement in dynamic MRI is not reproducible: illustration with a simple phantom. | |
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MedLine Citation:
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PMID: 11469929 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The goal of this work was to verify in a phantom study the necessity of a calibration method for comparison in dynamic contrast-enhanced magnetic resonance imaging (MRI) examinations. A perspex phantom with a dilution series of Gd-DTPA was used to measure the dynamic signal enhancement of a sequence. With nine MRI scanners from Bruker (0.23, 0.5, and 2 Tesla), Philips [0.5 and 1.5 Tesla (ACS-NT and S15)], and Siemens (0.2, 1.0, and 1.5 Tesla) one 2D FLASH and two 3D FLASH experiments were performed under identical measurement conditions. Under different measurement conditions (2D and 3D FLASH, TR, TE, FA) different characteristics in signal enhancement exist on a scanner. The same measurement conditions at different scanners (same magnetic field strength) also result in different signal enhancement. Dynamic contrast enhanced MRI examinations from different measurement conditions or scanners cannot be compared. To solve this problem a calibration is needed. |
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Authors:
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T Pabst; W Kenn; W A Kaiser; D Hahn |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The breast journal Volume: 7 ISSN: 1075-122X ISO Abbreviation: Breast J Publication Date: 2001 May-Jun |
Date Detail:
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Created Date: 2001-07-25 Completed Date: 2002-01-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9505539 Medline TA: Breast J Country: United States |
Other Details:
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Languages: eng Pagination: 166-70 Citation Subset: IM |
Affiliation:
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Institut für Röntgendiagnostik der Bayerischen Julius-Maximilians-Universität Würzburg, Würzburg, Germany. pabst@roentgen.uni-wuerzburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Neoplasms
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diagnosis* Calibration Contrast Media Female Gadolinium DTPA Humans Image Enhancement* Magnetic Resonance Imaging / methods* Phantoms, Imaging* Reproducibility of Results |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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