| Understanding the sequence of pulmonary injury in the extremely low birth weight, surfactant-deficient infant. | |
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MedLine Citation:
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PMID: 19592363 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human lung development begins around day 26 postconception and continues throughout early childhood. Many crucial events can affect this delicate tissue as it develops, leading to altered and abnormal growth and development of the lungs, thereby yielding a variety of morbidities and sometimes even mortality. Understanding the pathophysiology of lung injury in the extremely low birth weight neonate is essential when caring for these infants, especially during the first hours of life. This article provides bedside clinicians with foundational information related to acute lung injury and the sequence of events that can ultimately lead to neonatal chronic lung disease and bronchopulmonary dysplasia. |
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Authors:
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Steven W Peterson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Neonatal network : NN Volume: 28 ISSN: 1539-2880 ISO Abbreviation: Neonatal Netw Publication Date: 2009 Jul-Aug |
Date Detail:
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Created Date: 2009-07-13 Completed Date: 2009-10-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8503921 Medline TA: Neonatal Netw Country: United States |
Other Details:
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Languages: eng Pagination: 221-9; quiz 255-8 Citation Subset: N |
Affiliation:
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Pediatrics/Pediatric IntensiveCare, Stormont-Vail HealthCare, 1500 Sw 10th Street, Topeka, KS 66604, USA. stpeters@stormontvail.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Lung Injury
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etiology*,
physiopathology,
therapy Airway Resistance / physiology Barotrauma / complications Bronchopulmonary Dysplasia / etiology, prevention & control Disease Progression Free Radicals / adverse effects Humans Infant, Extremely Low Birth Weight* Infant, Newborn Infant, Premature, Diseases / etiology*, physiopathology, therapy Intensive Care, Neonatal / methods Lung / anatomy & histology, embryology, growth & development Lung Diseases / etiology, prevention & control Neonatal Nursing / methods Oxygen Inhalation Therapy / adverse effects Pulmonary Surfactants* / chemistry Respiratory Distress Syndrome, Newborn / diagnosis, etiology*, physiopathology, therapy Risk Factors Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Free Radicals; 0/Pulmonary Surfactants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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