| Understanding the link between the IL-6 cytokine family and pregnancy: implications for future therapeutics. | |
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MedLine Citation:
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PMID: 21895473 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cytokines are involved in almost all processes during the menstrual cycle, the fertilization period and pregnancy. They are expressed in numerous reproduction-related body fluids and tissues. Disorders of cytokine expression patterns may cause pregnancy pathologies. Therefore, cytokines have the potential as new biomarkers in different body compartments for a variety of such pathologies. Furthermore, cytokines may also serve to treat fertility and pregnancy disorders. The IL-6-like family of cytokines is an intensively investigated group of cytokines with well-accepted functions in fertility and pregnancy. This article summarizes current knowledge on IL-6-like cytokines in regard of their role in reproduction and their potential for new strategies in the treatment of reproductive pathologies. |
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Authors:
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Udo R Markert; Diana M Morales-Prieto; Justine S Fitzgerald |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of clinical immunology Volume: 7 ISSN: 1744-8409 ISO Abbreviation: Expert Rev Clin Immunol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101271248 Medline TA: Expert Rev Clin Immunol Country: England |
Other Details:
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Languages: eng Pagination: 603-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics, University Hospital of Jena, Bachstrasse 18, 07743 Jena, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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