| Understanding Lynch syndrome: implications for nursing. | |
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MedLine Citation:
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PMID: 17623626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Colorectal cancer (CRC) is the second-leading cause of cancer-related death in the United States. Approximately 10% of CRC is hereditary, and hereditary nonpolyposis CRC (HNPCC), or Lynch syndrome I, is the most common form. Lynch syndrome I is characterized by onset at an early age, poor differentiation, predominance of proximal tumors, and an excess of synchronous and metachronous tumors. In Lynch syndrome II, patients exhibit Lynch syndrome I features and also have extracolonic cancers. Lynch syndrome is an inherited autosomal dominant disorder caused by a germline mutation in one of several genes responsible for DNA mismatched repair. Amsterdam I criteria, Amsterdam II criteria, and Bethesda guidelines are the international diagnostic criteria for Lynch syndrome. Nursing care for patients with Lynch syndrome includes identifying patients who would benefit from genetic counseling, providing education, and assessing and meeting patient psychosocial needs. |
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Authors:
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Eileen Bannon; Elizabeth Ann Coleman |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical journal of oncology nursing Volume: 11 ISSN: 1092-1095 ISO Abbreviation: Clin J Oncol Nurs Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-07-11 Completed Date: 2007-08-17 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 9705336 Medline TA: Clin J Oncol Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 423-7 Citation Subset: N |
Affiliation:
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Penn State Cancer Institute, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA. ebannon@hmc.psu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Psychological Age of Onset Attitude to Health Colorectal Neoplasms, Hereditary Nonpolyposis* / diagnosis, genetics, psychology, therapy Counseling DNA Mismatch Repair Family / psychology Female Genetic Counseling Genetic Testing Germ-Line Mutation Grief Humans Microsatellite Repeats / genetics Middle Aged Nurse's Role* Nursing Assessment Oncologic Nursing / organization & administration* Patient Education as Topic Pedigree Practice Guidelines as Topic Social Support |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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