| Underlying diseases and co-factors in patients with severe chronic pruritus: a 3-year retrospective study. | |
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MedLine Citation:
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PMID: 17989889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic pruritus is a symptom of many diseases, with studies pending investigating its prevalence or incidence. The aim of this study was to describe the characteristics of the underlying diseases in a large number of patients. A total of 263 patients (110 men, 153 women; age range 8-95 years; mean 55.9 years) were included in the study. The following data were collected from patients presenting over a 3-year period: gender, age, history, skin lesions, laboratory, histological and radiological investigations. An underlying dermatosis was identified in 41.8% of patients, a systemic disease including unidentified neoplasms in 13.3% and a neurological disorder in 0.4%. No disease was found in 44.5% of patients. Among the patients in whom no disease was found, 55.6% of the, mainly elderly, patients had an accumulation of many co-factors, suggesting an own subgroup with multifactorial origin for the pruritus. The distribution and type of secondary scratch lesions gave no clue as to the underlying disease. In conclusion, patients with chronic pruritus present a inhomgeneous collective with different underlying diseases, including malignancy, necessitating thorough investigation. |
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Authors:
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Franz Sommer; Peter Hensen; Barbara Böckenholt; Dieter Metze; Thomas A Luger; Sonja Ständer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 87 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 2007 |
Date Detail:
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Created Date: 2007-11-08 Completed Date: 2008-02-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: Sweden |
Other Details:
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Languages: eng Pagination: 510-6 Citation Subset: IM |
Affiliation:
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Clinical Neurodermatology, Department of Dermatology, University of Münster, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Candidiasis / complications Child Chronic Disease Comorbidity Drug Therapy / adverse effects Endocrine System Diseases / complications Female Hematologic Diseases / complications Humans Male Middle Aged Neoplasms / complications Pruritus / etiology*, pathology Retrospective Studies Skin Diseases / complications Statistics, Nonparametric |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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