| Underlying cardiomyopathy in patients with ST-segment elevation in the right precordial leads. | |
| | |
MedLine Citation:
|
PMID: 16723793 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Ventricular fibrillation (VF) and sudden death (SD) may occur in patients with ST-segment elevation in the right precordial leads. The mechanism of such events is unclear, so the aim of the present study was to assess whether there is an underlying morphological or pathological abnormality in these patients. METHODS AND RESULTS: Fourteen consecutive patients (44+/-10 years old, all male) with ST-segment elevation of more than 2 mm in the right precordial leads underwent a cardiac evaluation, including right ventriculography and endomyocardial biopsy. The ST-segment changes after the administration of sodium-channel blockers were also evaluated. Two patients survived documented VF, 11 patients had chest pain or tightness, and another patient had a history of syncope. Only 1 patient had a family history of premature SD. The coronary angiograms were normal in all the patients. VF was induced in 5 patients (36%). Wall motion abnormalities of the right ventricle were detected in 4 patients (29%) and endomyocardial biopsy revealed features of cardiomyopathy in 7 patients (50%). In total, 9 (64%) of 14 patients exhibited wall motion abnormalities and/or pathologic findings. CONCLUSIONS: Underlying cardiomyopathy was present in more than half of the present patients with ST-segment elevation in the right precordial leads. |
| | |
Authors:
|
Hyungseop Kim; Yongkeun Cho; Yonghwi Park; Hyunsang Lee; Hyunjae Kang; Deuk-Young Nah; Taein Park; Dong Heon Yang; Hun Sik Park |
Related Documents
:
|
10567813 - Prolongation of the frequency-corrected qt dispersion following cerebral strokes with i... 522233 - Experimental study of cardiomyopathy induced by glucocorticoids. 17033333 - Chronic pancreatitis. |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 70 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2006 Jun |
Date Detail:
|
Created Date: 2006-05-25 Completed Date: 2006-07-07 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
|
Languages: eng Pagination: 719-25 Citation Subset: IM |
Affiliation:
|
Division of Cardiology, Department of Internal Medicine, Kyungpook National University, Taegu, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Biopsy Cardiomyopathies / drug therapy, pathology*, physiopathology*, ultrasonography Coronary Angiography Death, Sudden / pathology Echocardiography Electrocardiography* Heart / physiopathology Heart Ventricles / pathology, physiopathology, ultrasonography Humans Male Middle Aged Sodium Channel Blockers / administration & dosage Ventricular Fibrillation / drug therapy, pathology, physiopathology, ultrasonography |
| Chemical | |
Reg. No./Substance:
|
0/Sodium Channel Blockers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nuclear hypertrophy reflects increased biosynthetic activities in myocytes of human hypertrophic hea...
Next Document: Initial and midterm results for repair of aortic diseases with handmade stent grafts.