| Uncompacted myelin lamellae in two cases of peripheral neuropathy. | |
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MedLine Citation:
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PMID: 6310926 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Peripheral nerve biopsies from two patients with chronic sensorimotor neuropathy were studied. The first case was a non-Hodgkin malignant lymphoma and did not show any dysglobulinemia. The second case had a benign monoclonal gammopathy IgG, Lambda type. Direct immunofluorescence showed no deposits in the first case and slight deposits of anti IgG sera on a few myelinated fibers in the second case. There were numerous fibers showing uncompacted myelin lamellae, 7% in the first case and 4% in the second case. Some of these fibers had axons containing more tubules than filaments. The very few cases reported on neuropathies showing that uncompacted myelin lamellae were frequently associated with dysglobulinemic neuropathy. However, this ultrastructural abnormality of the myelin sheath can be observed without any dysglobulinemia. |
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Authors:
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C Vital; C Brechenmacher; J Reiffers; A Lagueny; R Massonnat; J Julien; A Broustet; L Mouton |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta neuropathologica Volume: 60 ISSN: 0001-6322 ISO Abbreviation: Acta Neuropathol. Publication Date: 1983 |
Date Detail:
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Created Date: 1983-10-21 Completed Date: 1983-10-21 Revised Date: 2007-11-09 |
Medline Journal Info:
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Nlm Unique ID: 0412041 Medline TA: Acta Neuropathol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 252-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Axons / ultrastructure Chronic Disease Female Humans Hypergammaglobulinemia / pathology Immunoglobulin G Lymphoma / pathology Microscopy, Electron Myelin Sheath / ultrastructure Nerve Fibers, Myelinated / ultrastructure Peripheral Nervous System Diseases / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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