| Uncommon vancomycin-induced side effects. | |
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MedLine Citation:
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PMID: 12204187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the red man syndrome . Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major associated with neutropenia. |
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Authors:
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Jaime Luis Lopes Rocha; William Kondo; Maria Inêz Domingues Kuchiki Baptista; Clovis Arns Da Cunha; Luzmila Terezinha Flenik Martins |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases Volume: 6 ISSN: 1413-8670 ISO Abbreviation: Braz J Infect Dis Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-09-02 Completed Date: 2003-01-15 Revised Date: 2007-04-24 |
Medline Journal Info:
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Nlm Unique ID: 9812937 Medline TA: Braz J Infect Dis Country: Brazil |
Other Details:
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Languages: eng Pagination: 196-200 Citation Subset: IM |
Affiliation:
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Division of Infectious Disease, Nossa Senhora das Graças Hospital, Curitiba, Paraná, Brazil. jaimeluis@b.com.br |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents / adverse effects*, therapeutic use Anti-Infective Agents / therapeutic use Eosinophilia / chemically induced Erythema / chemically induced* Female Fever / chemically induced Hip Prosthesis Humans Methicillin Resistance Middle Aged Neutropenia / chemically induced* Ofloxacin / therapeutic use Prosthesis-Related Infections / drug therapy Pruritus / chemically induced Staphylococcus / isolation & purification Syndrome Vancomycin / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Infective Agents; 1404-90-6/Vancomycin; 82419-36-1/Ofloxacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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