Document Detail

Uncommon presentation of nasopharyngeal extramedullary plasmacytoma: a case report and literature review.
MedLine Citation:
PMID:  20681370     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We report an exceptional presentation of extramedullary plasmacytoma of the nasopharynx without bone marrow involvement or other characteristics of multiple myeloma. METHOD: Case report and a review of the world literature concerning the clinical presentation, histopathological features, optimal treatment and prognosis of nasopharyngeal extramedullary plasmacytoma. RESULTS: Reports of patients with symptomatic extramedullary plasmacytomas of the nasopharynx eventually being documented with histopathological evidence are not uncommon; however, the converse appears to be an extremely rare event. The patient was completely asymptomatic and following a paroxysm of coughing, expectorated a polypoidal nodule, which on histopathological investigation had features suggestive of extramedullary plasmacytoma. CONCLUSION: Although these tumours commonly present with significant nasal symptoms, this exceptional presentation in an asymptomatic patient has never been previously reported. Unusual presentations of rare tumours can pose considerable diagnostic dilemmas to both the surgeon and histopathologist. Awareness of these rarities is important to ensure the best patient care.
A Manganaris; B Conn; S Connor; R Simo
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  B-ENT     Volume:  6     ISSN:  1781-782X     ISO Abbreviation:  B-ENT     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-04     Completed Date:  2010-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101247842     Medline TA:  B-ENT     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  143-6     Citation Subset:  IM    
Department of Otorhinolaryngology--Head and Neck Surgery, Guy's and St Thomas' Hospital NHS Foundation Trust, Guy's Hospital, London SE1 9RT, UK.
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MeSH Terms
Nasopharyngeal Neoplasms / diagnosis*,  pathology,  radiography
Plasmacytoma / diagnosis*
Tomography, X-Ray Computed

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