| Unanchoring integrins in focal adhesions. | |
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MedLine Citation:
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PMID: 23033047 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix. A detailed analysis of integrin dynamics now indicates that focal-adhesion-associated integrins constantly switch between active and immobilized, and unbound and free-diffusing states, with different fibronectin-binding integrin heterodimers showing distinct focal-adhesion dynamics. |
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Authors:
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Johanna Ivaska |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nature cell biology Volume: 14 ISSN: 1476-4679 ISO Abbreviation: Nat. Cell Biol. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890575 Medline TA: Nat Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 981-3 Citation Subset: IM |
Affiliation:
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Turku Centre for Biotechnology, University of Turku, and VTT Technical Research Centre of Finland, Turku 20520, Finland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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