Document Detail


Unanchoring integrins in focal adhesions.
MedLine Citation:
PMID:  23033047     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix. A detailed analysis of integrin dynamics now indicates that focal-adhesion-associated integrins constantly switch between active and immobilized, and unbound and free-diffusing states, with different fibronectin-binding integrin heterodimers showing distinct focal-adhesion dynamics.
Authors:
Johanna Ivaska
Related Documents :
8908427 - Endothelial morphological and functional evaluation after cataract surgery.
11709267 - Linear posterior capsule opacification with the acrysof intraocular lens.
22360627 - Tissue factor-positive monocytes in children with sickle cell disease: correlation with...
24357647 - Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survi...
6479237 - Adhesive and migratory behavior of normal and sulfate-deficient sea urchin cells in vitro.
25261667 - Expression of vascular endothelial growth factor and microvascular density assessment i...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature cell biology     Volume:  14     ISSN:  1476-4679     ISO Abbreviation:  Nat. Cell Biol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890575     Medline TA:  Nat Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  981-3     Citation Subset:  IM    
Affiliation:
Turku Centre for Biotechnology, University of Turku, and VTT Technical Research Centre of Finland, Turku 20520, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Integrating insulin secretion and ER stress in pancreatic ?-cells.
Next Document:  Connecting membrane traffic to ESCRT and the final cut.