Document Detail

Umbilical venous blood flow measurement: accuracy and reproducibility.
MedLine Citation:
PMID:  18618412     Owner:  NLM     Status:  MEDLINE    
Umbilical venous blood flow could be considered a direct and physiological measurement of vascular placental function, representing the quantity of oxygen and nutrients reaching the fetus. The advent of high-technology ultrasound and pulsed Doppler has overcome some of the limitations of early studies. Indeed, Doppler measurement of umbilical venous blood flow has been found to be accurate when compared with several gold standards for in-vivo flow calculation. Nevertheless, small errors in volume flow components, the vessel area and the mean velocity, result in large errors in the calculation of volume flow. Therefore, technique standardization is of paramount importance. Validation studies in animal models have demonstrated accurate venous blood flow measurements by estimating the vessel's cross-sectional area from perpendicular views of longitudinal sections of free-floating portions of the cord. On the other hand, estimation of the mean velocity from the maximum velocity, rather than using the intensity-weighted mean velocity, is less software-dependent and more clearly defined, yielding estimates with more predictable and systematic errors. By adhering to stringent methodological recommendations, umbilical venous blood flow calculation has moderate to good intra- and interobserver reproducibility. Having been found to be accurate and reproducible, further studies are required to establish the clinical value of umbilical vein flow measurement.
F Figueras; S Fernández; E Hernández-Andrade; E Gratacós
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  32     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-28     Completed Date:  2009-02-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  587-91     Citation Subset:  IM    
Maternal-Fetal Medicine Department, Obstetrics, Gynaecology and Neonatology Institute, ICGON Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
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MeSH Terms
Blood Flow Velocity
Reproducibility of Results
Ultrasonography, Doppler / methods
Ultrasonography, Prenatal / methods
Umbilical Veins / anatomy & histology,  physiology*,  ultrasonography*

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