| Umbilical vein blood flow at 11 + 0 to 13 + 6 weeks of gestation. | |
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MedLine Citation:
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PMID: 20044876 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To establish reference intervals for fetal umbilical vein (UV) diameter, UV time averaged maximum velocity (TAMXV) and UV flow (UVBF) at 11 + 0 to 13 plus; 6 weeks of gestation and to determine the intraobserver reliability of these measurements. METHODS: We considered, in a cross-sectional study, 162 fetuses from uncomplicated singleton pregnancies at 11 + 0 to 13 + 6 weeks of gestation. UV diameter and TAMXV were measured in its intraabdominal portion by real-time and Doppler ultrasonography and UVBF calculated. Relationships between these parameters and fetal crown rump length were tested by regression analysis. In 25 cases UVBF was measured twice by the same investigator and the intraobserver agreement of these measurements was calculated. RESULTS: A significant increase was evidenced in the gestational age period considered in UV diameter (r = 0.729, p < 0.0001), TAMXV (r = 0.691, p < 0.0001) and UVBF (r = 0.777, p < 0.0001). UVBF increased from 2.26 ml/min at 11 weeks to 15.62 ml/min at 13 + 6 weeks of gestation. The intraobserver ICCs were 0.96, 0.92 and 0.88, respectively, for UV diameter, TAMXV and UVBF. CONCLUSIONS: In normal fetuses, UV diameter, TAMVX and flow increase between 11 + 0 and 13 + 6 weeks of gestation. In this gestational age interval, the calculation of UV blood flow and its components shows an intraobserver agreement reliable enough for clinical use. |
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Authors:
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Giuseppe Rizzo; Alessandra Capponi; Maria Elena Pietrolucci; Domenico Arduini |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 23 ISSN: 1476-4954 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-12 Completed Date: 2010-06-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: England |
Other Details:
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Languages: eng Pagination: 315-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Universit? di Roma, Tor Vergata, Roma, Italy. giuseppe.rizzo@uniroma2.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity Cross-Sectional Studies Female Gestational Age* Humans Pregnancy Ultrasonography, Prenatal Umbilical Veins / blood supply* |
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