Document Detail

Umbilical cord blood gases and mortality and morbidity in the very low birth weight infant.
MedLine Citation:
PMID:  1923194     Owner:  NLM     Status:  MEDLINE    
Umbilical cord blood gas values and morbidity and mortality were correlated in 191 very low birth weight (VLBW) infants (500-1500 g). The mean umbilical arterial pH and base excess differed significantly between survivors and non-survivors. The presence of at least moderate acidosis (arterial pH 7.15 or lower) was related significantly to mortality, particularly in infants younger than 26 weeks. The mean cord blood gas values did not predict the presence or severity of hyaline membrane disease or intraventricular hemorrhage, but Apgar scores did. Bronchopulmonary dysplasia, neurologic sequelae, necrotizing enterocolitis, and sepsis also did not correlate with mean cord gas values, but neither did Apgar scores. Furthermore, the severity and type of acidosis did not relate to morbidity. Combining cord blood gases and Apgar scores did not help predict morbidity, which was not surprising because cord pH values correlated poorly with Apgar scores (all r values less than or equal to 0.26). We urge caution in interpreting cord gases as predictors of morbidity in the VLBW infant.
J U Hibbard; M C Hibbard; M P Whalen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  78     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1991-11-20     Completed Date:  1991-11-20     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  768-73     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Chicago, Illinois.
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MeSH Terms
Acidosis / epidemiology
Apgar Score
Bacterial Infections / epidemiology
Birth Weight
Brain Diseases / epidemiology
Bronchopulmonary Dysplasia / epidemiology
Carbon Dioxide / blood*
Cerebral Hemorrhage / epidemiology
Chicago / epidemiology
Enterocolitis, Pseudomembranous / epidemiology
Fetal Blood / chemistry*
Gestational Age
Hyaline Membrane Disease / epidemiology
Infant Mortality*
Infant, Low Birth Weight*
Infant, Newborn
Infant, Newborn, Diseases / epidemiology*
Oxygen / blood*
Survival Rate
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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