Document Detail

Umbilical artery velocity waveforms before and after chorionic villus sampling.
MedLine Citation:
PMID:  7845886     Owner:  NLM     Status:  MEDLINE    
Because a vascular aetiology has been suggested for the limb and oromandibular defects described after chorionic villus sampling (CVS), to determine whether transabdominal (TA) CVS causes noticeable changes in umbilical artery velocity waveforms in first-trimester pregnancies, the pulsatility index (PI) of the umbilical artery was evaluated before and after TA-CVS in 175 pregnancies sampled between 10.0 and 13.0 weeks' gestation. In 139 uncomplicated pregnancies, the mean PI values (with 95 per cent confidence interval) were before TA-CVS 2.751 (2.692-2.809), after 10 min 2.723 (2.697-2.809), and after 1 h 2.781 (2.722-2.840). There were no significant changes in PI relative to the CVS procedure either in pregnancies with an abnormal result or in those ending in spontaneous abortion. Our data do not support any statistically significant change in umbilical artery PI relative to TA-CVS in first-trimester pregnancies. This procedure, despite its invasive character, does not appear to affect the feto-placental circulation.
R M Ibba; G Monni; G Olla; A Cao
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  14     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-03-08     Completed Date:  1995-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  799-802     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Università degli Studi di Cagliari, Ospedale Regionale per le Microcitemie, Sardinia, Italy.
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MeSH Terms
Blood Flow Velocity
Chorionic Villi Sampling*
Follow-Up Studies
Pregnancy Outcome
Pregnancy Trimester, First / physiology
Ultrasonography, Doppler, Pulsed
Ultrasonography, Prenatal
Umbilical Arteries / physiology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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