Document Detail


Umbilical artery and ductal blood flow velocities in patients treated with aspirin and prednisone for presence of anticardiolipin antibody.
MedLine Citation:
PMID:  8492375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifteen patients with previous pregnancy losses and positive plasma anticardiolipin antibody (ACA) were treated with prednisone (15 mg/day) and aspirin (80 mg/day). We measured Doppler velocimetries of umbilical artery and ductus arteriosus at intervals of 2 to 3 weeks starting from 20 weeks of gestation until delivery. Umbilical artery systolic/diastolic ratios (S/D) and maximum systolic velocities of ductus arteriosus did not differ from normal values. There were no poor outcomes in the treated group. ACA positive patients with previous poor pregnancy outcome when treated with prednisone and aspirin have umbilical artery and ductal flow velocities similar to those of the normal population.
Authors:
I Forouzan; A W Cohen; C Lindenbaum; P Samuels
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  12     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-06-11     Completed Date:  1993-06-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia 19104.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Habitual / drug therapy,  immunology,  physiopathology*
Antibodies, Anticardiolipin*
Aspirin / therapeutic use
Blood Flow Velocity
Ductus Arteriosus / physiology*
Female
Fetus / physiology*
Humans
Prednisone / therapeutic use
Pregnancy
Prospective Studies
Ultrasonography, Prenatal*
Umbilical Arteries / physiology*
Chemical
Reg. No./Substance:
0/Antibodies, Anticardiolipin; 50-78-2/Aspirin; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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