| Ultrastructure of the mammary gland in lactating rats after local implantation of oestrogen. | |
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MedLine Citation:
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PMID: 1172519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cannulae containing oestrogen were implanted in the mammary glands of rats on the first day after parturition and lactation assessed by daily measurements of the litter weight. Sham-implanted and intact lactating rats were used as controls. A clear-cut inhibition of the milk yield was observed in the oestrogen-implanted group. Mammary tissue was processed for fine structural study after 4, 8 or 10 days. The initial phase showed milk stasis and secretion of colostrum progressively involving the alveoli and culminating in regression of the mammary tissue. Disappearance of myofilaments from the myoepithelial cells was consistently observed. Secretion of colostrum and mammary regression could be the result of the stasis produced by an abnormal dynamic state of the myoepithelial cell elicited by the steroid. |
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Authors:
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A J Zamora; A S Mendoza; V D Ramirez |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of endocrinology Volume: 66 ISSN: 0022-0795 ISO Abbreviation: J. Endocrinol. Publication Date: 1975 Aug |
Date Detail:
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Created Date: 1975-12-11 Completed Date: 1975-12-11 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0375363 Medline TA: J Endocrinol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 177-82 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Colostrum / secretion Endoplasmic Reticulum / ultrastructure Epithelial Cells Epithelium / ultrastructure Estradiol / pharmacology* Female Golgi Apparatus / ultrastructure Lactation* Lipids / analysis Mammary Glands, Animal / drug effects, secretion, ultrastructure* Milk / secretion Mitochondria / ultrastructure Pregnancy Rats Vacuoles / ultrastructure |
| Chemical | |
Reg. No./Substance:
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0/Lipids; 50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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