Document Detail


Ultrastructure of connective tissue of eye drainage system in ophthalmic hypertension associated with primary juvenile glaucoma.
MedLine Citation:
PMID:  19039948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In primary juvenile glaucoma, the connective tissue of the juxtacanalicular zone and sclera undergo constant reorganization because of incessant synthesis and degradation of extracellular matrix components with pronounced fluctuations of electron density of collagen fibrils. Destructive changes in the perivascular nerve trunks were detected at all stages of the glaucoma process, including the initial stages: numerous large foci of cytoplasmic organelle destruction with the formation of autophagosomes and residual bodies predominated in the cytoplasm of myelinated axons of nerve cells.
Authors:
O N Kuleshova; G I Nepomnyashchikh; S V Aidagulova
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  145     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-12-01     Completed Date:  2009-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  374-6     Citation Subset:  IM    
Affiliation:
Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. pathol@soramn.ru
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Connective Tissue / ultrastructure*
Female
Glaucoma / pathology*
Glaucoma, Open-Angle / pathology
Humans
Male
Middle Aged
Ocular Hypertension / pathology
Sclera / pathology,  ultrastructure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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