Document Detail


Ultrastructure of the collagen fibril. II. Evidence of the spiral organization of the fibril.
MedLine Citation:
PMID:  747226     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Unfixed tissue from the human ovary, the tail tendon and skin from the tail of rats are incubated in 5% solutions of uranyl acetate. The collagen fibrils of all tissues are decomposed and display an obvious tridimensional spiral structure on all levels. The fibril is a complex biopolymer constructed out of filaments, surrounded by and associated with an amorphous cementing matrix. The filaments consist of 3 to 5 subfilaments with a thickness of 30--45 A spirally wound around one another. The filaments are twisted along the length of the axis of the fibril under a definite angle of inclination and a pitch of the spiral equal to 1.04--1.12 micrometer for the ovary and from 2.6 to over 5.6 micrometer for the tail tendon. The cross striations seem to spring out of the nodular thickenings along the filaments. Bridge-like connections corresponding to the separate striations are established between adjacent fibrils. A new tridimensional structure model of the collagen fibrils is proposed.
Authors:
R Petkov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anatomischer Anzeiger     Volume:  144     ISSN:  0003-2786     ISO Abbreviation:  Anat Anz     Publication Date:  1978  
Date Detail:
Created Date:  1979-05-23     Completed Date:  1979-05-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370541     Medline TA:  Anat Anz     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  485-501     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Collagen*
Connective Tissue / metabolism,  ultrastructure*
Female
Humans
Ovary / ultrastructure
Rats
Skin / ultrastructure
Tail / ultrastructure
Tendons / ultrastructure
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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