Document Detail


Ultrastructure of bronchial epithelium in children with chronic or recurrent respiratory diseases.
MedLine Citation:
PMID:  6983456     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ultrastructure of the bronchial epithelium in three children with recurrent bronchopneumonia, four patients with cystic fibrosis and two with Kartagener's syndrome was studied. The children with recurrent bronchopneumonia and those with Kartagener's syndrome had mostly changes in the pseudostratified ciliated epithelium, and two of them had ultrastructural signs of developing squamous metaplasia. Developed stratified squamous epithelium was found in three of four patients with cystic fibrosis and in one patient with recurrent bronchopneumonia. The squamous epithelium showed striking pathological changes, but, only the oldest patient with cystic fibrosis showed signs of onset of keratinization. Both patients with Kartagener's syndrome had the defect of dynein arms typical of the immotile-cilia syndrome. In the youngest patient the partial absence of dynein arms was combined with a defect in the radial structures of the axonemes.
Authors:
V Konrádová; V Vavrová; Z Hlousková; M Copová; A Tománek; J Houstĕk
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of respiratory diseases     Volume:  63     ISSN:  0106-4339     ISO Abbreviation:  Eur J Respir Dis     Publication Date:  1982 Nov 
Date Detail:
Created Date:  1983-02-25     Completed Date:  1983-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006891     Medline TA:  Eur J Respir Dis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  516-25     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Bronchi / ultrastructure*
Bronchial Diseases / pathology
Child
Child, Preschool
Chronic Disease
Cystic Fibrosis / pathology
Epithelium / ultrastructure
Female
Humans
Kartagener Syndrome / pathology
Male
Microscopy, Electron
Pneumonia / pathology
Recurrence
Respiratory Tract Diseases / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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