Document Detail

Ultrastructure of atrial and ventricular myocytes of newborn rats: evidence for the existence of specific atrial granule-like organelles in the ventricle.
MedLine Citation:
PMID:  2535289     Owner:  NLM     Status:  MEDLINE    
The present study examined the ultrastructure of atrial and ventricular myocytes from the heart of newborn rats. It was found that, despite former reports stating that ventricular myocytes in adults do not contain cytoplasmic granules, specific atrial granule-like organelles are present in the ventricles of rats at birth. The presence of these granules together with the relatively underdeveloped contractile apparatus and extensive Golgi complex suggests that the ventricular, like the atrial, myocytes may have an endocrine function before or at birth. Further study is required to determine whether these ventricular cytoplasmic granules contain the same atrial natriuretic peptide species known to be present in the atrial specific granules.
S L Venance; S C Pang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Histology and histopathology     Volume:  4     ISSN:  0213-3911     ISO Abbreviation:  Histol. Histopathol.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1992-05-12     Completed Date:  1992-05-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8609357     Medline TA:  Histol Histopathol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  325-33     Citation Subset:  IM    
Department of Anatomy, Queen's University, Kingston, Ontario, Canada.
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MeSH Terms
Animals, Newborn / physiology*
Atrial Natriuretic Factor / physiology
Cell Communication
Cytoplasmic Granules / ultrastructure*
Golgi Apparatus / physiology,  ultrastructure
Heart Atria / ultrastructure*
Heart Ventricles / ultrastructure*
Microscopy, Electron
Organelles / ultrastructure*
Rats, Inbred WKY
Reg. No./Substance:
85637-73-6/Atrial Natriuretic Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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