| Ultrastructural study of the local changes induced in the white rat by the venom of Bothrops picadoi of Costa Rica | |
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MedLine Citation:
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PMID: 6729845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pathogenesis of local lesions induced by Bothrops picadoi venom was studied at the electron microscopic level. White mice were injected i.m. with 100 micrograms of venom. A strong hemorrhagic action was the earliest and most prominent local effect observed in this study. In skeletal muscle fibers, rupture of the sarcolemma was observed and myofibril structure was drastically affected, showing amorphous masses of myofilaments. Myelin layers in many axons were disorganized. |
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Authors:
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O Arroyo; L Cerdas |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Toxicon : official journal of the International Society on Toxinology Volume: 22 ISSN: 0041-0101 ISO Abbreviation: Toxicon Publication Date: 1984 |
Date Detail:
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Created Date: 1984-07-02 Completed Date: 1984-07-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1307333 Medline TA: Toxicon Country: ENGLAND |
Other Details:
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Languages: spa Pagination: 301-5 Citation Subset: IM |
Vernacular Title:
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Estudio ultraestructural de las alteraciones locales inducidas en ration blanco por el veneno de Bothrops picadoi de Costa Rica. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Axons / ultrastructure Crotalid Venoms / toxicity* Hemorrhage / pathology Neurons / ultrastructure Rats Skin / pathology Snake Bites / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Crotalid Venoms |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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