Document Detail


Ultrastructural study of the liver in argininosuccinase deficiency.
MedLine Citation:
PMID:  3786262     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The liver of a 19-year-old woman with argininosuccinase deficiency was studied ultrastructurally under conditions for excellent tissue fixation. Dilated smooth endoplasmic reticulum and mitochondrial crystalloids were the most prominent abnormalities found. These features were compared to fine-structural abnormalities found in other disorders of the Krebs-Henseleit pathway. No change was considered specific or related to subcellular enzyme localization.
Authors:
H Travers; J S Reed; J A Kennedy
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric pathology / affiliated with the International Paediatric Pathology Association     Volume:  5     ISSN:  0277-0938     ISO Abbreviation:  Pediatr Pathol     Publication Date:  1986  
Date Detail:
Created Date:  1986-12-31     Completed Date:  1986-12-31     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8303527     Medline TA:  Pediatr Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-18     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Argininosuccinic Aciduria*
Female
Humans
Liver / ultrastructure*
Lyases / deficiency*
Microscopy, Electron
Chemical
Reg. No./Substance:
EC 4.-/Lyases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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