Document Detail

Ultrastructural studies on the effect of fenthion on pituitary (GTH cells) and testis of Glossogobius giuris. (HAM) during breeding phase.
MedLine Citation:
PMID:  16114458     Owner:  NLM     Status:  MEDLINE    
Pesticide (fenthion) which finds its way into water bodies, bring about physiological changes in aquatic animals, via histomorphology and histopathology of various tissues. In fishes, it induces disorders including hyposecretion of gonadotropin in the PPD and regression of gonads. Light microscopic studies were made on control and treated pituitary (gonadotropin secreting cells-GTH) and testis of Glossogobius giuris (HAM) during spawning phase after exposing them to different (0.05 to 0.5 ppm) sub-lethal concentration of fenthion for a short-term period (24 to 96 hrs). The results indicated alteration in normal histology of gonadotropin secreting cells and testis, reduction in number of sperms and degranulation of GTH cells under light microscopy. Degeneration and fragmentation of cytoplasmic organelles was noticed in GTH cells under electron microscope, with the increase in the sub-lethal concentration of fenthion. Significance of the results is discussed in detail in the manuscript.
Bela Zutshi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of environmental biology / Academy of Environmental Biology, India     Volume:  26     ISSN:  0254-8704     ISO Abbreviation:  J Environ Biol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-08-23     Completed Date:  2005-12-06     Revised Date:  2009-03-09    
Medline Journal Info:
Nlm Unique ID:  8300544     Medline TA:  J Environ Biol     Country:  India    
Other Details:
Languages:  eng     Pagination:  31-6     Citation Subset:  IM    
Department of Zoology, Jnana Bharathi, Bangalore University, 560 056-Bangalore, India.
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MeSH Terms
Fenthion / toxicity*
Insecticides / toxicity*
Microscopy, Electron
Pituitary Gland / drug effects*,  ultrastructure
Testis / drug effects*,  ultrastructure
Reg. No./Substance:
0/Insecticides; 55-38-9/Fenthion

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