Document Detail


Ultrastructural pathology of eccrine sweat gland epithelial cells in globoid cell leukodystrophy.
MedLine Citation:
PMID:  8389389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three of four children were recognized by deficient beta-galactocerebrosidase activities as having globoid cell leukodystrophy inclusions in sweat gland epithelial cells, similar in ultrastructure to those seen in Schwann cells. This observation in globoid cell leukodystrophy emphasizes the need to include sweat gland epithelial cells in examinations of skin in globoid cell leukodystrophy, as well as in any neurometabolic disorder.
Authors:
H H Goebel; S Kimura; K Harzer; H Klein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  8     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-07-08     Completed Date:  1993-07-08     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  171-4     Citation Subset:  IM    
Affiliation:
Division of Neuropathology, University of Mainz, Germany.
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MeSH Terms
Descriptor/Qualifier:
Biopsy
Child
Child, Preschool
Eccrine Glands / pathology*
Epithelium / pathology
Female
Humans
Inclusion Bodies / ultrastructure
Infant
Leukodystrophy, Globoid Cell / pathology*
Lipid Metabolism
Male
Microscopy, Electron
Skin / pathology
Vacuoles / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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