Document Detail


Ultrastructural morphometry of matrical changes induced by exercise and food restriction in the rat calcaneal tendon.
MedLine Citation:
PMID:  1440575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ultrastructural morphometry of collagen fibril populations in 24 calcaneal tendons obtained from 12 Fischer 344 rats were studied to elucidate matrical changes induced by food restriction and/or endurance exercise. Rats were randomly assigned to four equal groups: ad libitum control (AC), ad libitum exercise (AE), restricted diet control (RC) and restricted diet exercise (RE) groups. Beginning from 6 weeks of age, animals in the two food restriction groups were fed 60% of the mean food consumption of ad libitum fed rats. Then, starting from 6-7 months of age, the rats in the two exercise groups performed 40-50 min of treadmill running at 1.2-1.6 miles h-1 every day for a total of 10 weeks. Endurance training did not significantly alter body weight, but food restriction with or without exercise resulted in a significant loss of body weight. In ad libitum fed controls, food restriction alone did not significantly alter the mean collagen fibril CSA, but predisposed a preponderance of small-sized collagen fibrils. Endurance training per se induced a significant (32%) increase in mean fibril CSA (P less than 0.05), but this adaptive response to exercise was prevented by food restriction, as indicated by a 33% decline in fibril CSA (P less than 0.05). These findings demonstrate that dietary restriction modifies the adaptation of tendon collagen morphometry in response to endurance training, and that weight loss is better achieved with food restriction than endurance exercise.
Authors:
C S Enwemeka; L C Maxwell; G Fernandes
Related Documents :
2208145 - Protective effects of voluntary exercise during the postinitiation phase of pancreatic ...
6198045 - Nycthemeral variation in brain monoamines of syrian hamsters: relation to activity and ...
15264035 - Effect of strenuous maternal exercise before and during pregnancy on rat progeny renal ...
14695115 - Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obe...
18081505 - Arterial oxygen saturation and hemoglobin mass in postmenopausal untrained and trained ...
8088975 - Alternative design for radiologic guidance in video thoracoscopic surgery.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Tissue & cell     Volume:  24     ISSN:  0040-8166     ISO Abbreviation:  Tissue Cell     Publication Date:  1992  
Date Detail:
Created Date:  1992-12-02     Completed Date:  1992-12-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0214745     Medline TA:  Tissue Cell     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  499-510     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics and Rehabilitation, University of Miami School of Medicine and Research Service, Veterans Affairs Medical Center, FL 33146.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animal Nutritional Physiological Phenomena*
Animals
Collagen / biosynthesis,  ultrastructure
Diet
Male
Physical Conditioning, Animal*
Rats
Rats, Inbred F344
Specific Pathogen-Free Organisms
Tendons / ultrastructure*
Grant Support
ID/Acronym/Agency:
AG 01188/AG/NIA NIH HHS; AG 03417/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of exercise and food restriction on rat skeletal muscles.
Next Document:  Ultrastructural morphometry of membrane-bound intracytoplasmic collagen fibrils in tendon fibroblast...