| Ultrastructural localization of cisplatin in Ehrlich ascites tumor cells. | |
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MedLine Citation:
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PMID: 3359413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incorporation of cis-diammine Dichloro Platinum (II) (cisplatin) on the Ehrlich ascites carcinoma (EAT) cells has been studied in this paper. Ultrastructural study of cells treated 'in vivo' with cisplatin showed that a new treatment with this substance after fixation, blocks uranyl acetate staining with the consequent lack of heterochromatin contrast. |
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Authors:
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V Rodilla; J Pertusa; J A Pellicer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cancer letters Volume: 39 ISSN: 0304-3835 ISO Abbreviation: Cancer Lett. Publication Date: 1988 Mar |
Date Detail:
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Created Date: 1988-06-02 Completed Date: 1988-06-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600053 Medline TA: Cancer Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 179-83 Citation Subset: IM |
Affiliation:
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Department of Animal Biology, University of Valencia, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinoma, Ehrlich Tumor / analysis*, ultrastructure Cell Nucleus / analysis Cisplatin / analysis* DNA / analysis Female Mice Organometallic Compounds / diagnostic use Tissue Distribution |
| Chemical | |
Reg. No./Substance:
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0/Organometallic Compounds; 15663-27-1/Cisplatin; 541-09-3/uranyl acetate; 9007-49-2/DNA |
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