| Ultrastructural investigation of renomedullary interstitial cells in "endocrine kidney". | |
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MedLine Citation:
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PMID: 7471759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the renomedullary interstitial cells of rats with Selye's "endocrine kidney" in the phase of beginning hypertension there appeared bilateral stress hypergranulation and an ultrastructural pattern of intensive prostaglandin synthesis. In the interstitial tissue of the left medulla there appeared light and dense (fibroblast- or macrophage-like) cells. Along with the stabilization of hypertension a relative degranulation of interstitial cells in the right kidney and an absolute degranulation in the left kidney took place. Necrobiotic changes, appearing in the ischaemic kidney, reflected an exhaustion of morphological substrates of prostaglandin synthesis. The changes in the interstitial cells, possessing endocrine activity, present the decisive links in the genesis of experimental malignant hypertension in rats. |
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Authors:
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B L Anavi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cor et vasa Volume: 22 ISSN: 0010-8650 ISO Abbreviation: Cor Vasa Publication Date: 1980 |
Date Detail:
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Created Date: 1981-05-26 Completed Date: 1981-05-26 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372614 Medline TA: Cor Vasa Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 445-54 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aorta / pathology Aortic Diseases / pathology Constriction, Pathologic Hypertension, Renal / pathology* Hypertension, Renovascular / pathology* Ischemia Kidney / blood supply Kidney Medulla / ultrastructure* Male Rats |
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