| Ultrastructural and immunocytochemical definition of component neoplasms in an unusual gastro-oesophageal collision tumour. | |
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MedLine Citation:
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PMID: 3013748 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An unusual collision tumour (concrescence of two neighbouring independent neoplasms) is reported. One tumour was a small cell undifferentiated (oat cell) carcinoma of the lower oesophagus and the other was a gastro-oesophageal adenocarcinoma. There was little intermingling of the two patterns. The adenocarcinoma stained strongly positive for mucin and carcinoembryonic antigen (CEA), but the small cell carcinoma was negative for both and also argyrophil-negative; both were negative for neurone-specific enolase and common leukocyte antigen. Ultrastructural study showed extra-cellular glandular lumina lined by cells with apical microvilli and junctional complexes in the adenocarcinoma; primitive cells without tonofilaments or dense-core granules, and joined by rudimentary desmosomes were seen in the small cell carcinoma. Collision carcinomas may result from a carcinogenic stimulus affecting two neighbouring regions of mucosa or may simply be the chance apposition of two unrelated tumours. |
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Authors:
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S Purdy; E F Gaffney |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Histopathology Volume: 10 ISSN: 0309-0167 ISO Abbreviation: Histopathology Publication Date: 1986 May |
Date Detail:
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Created Date: 1986-08-14 Completed Date: 1986-08-14 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 7704136 Medline TA: Histopathology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 525-34 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology*,
ultrastructure Aged Aminosalicylic Acid / diagnostic use Carcinoma, Small Cell / pathology*, ultrastructure Esophageal Neoplasms / pathology*, ultrastructure Histocytochemistry Humans Immunoenzyme Techniques Male Microscopy, Electron Stomach Neoplasms / pathology*, ultrastructure |
| Chemical | |
Reg. No./Substance:
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65-49-6/Aminosalicylic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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