| Ultrastructural evidence for direct monosynaptic rubrospinal connections to motoneurons in Macaca mulatta. | |
MedLine Citation:
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PMID: 2465507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The magnocellularis division of the red nucleus of the Macaca mulatta, a midbrain structure involved in processing motor information, is known by light microscopic analysis to project, via the rubrospinal tract, to the contralateral intermediate horn of the spinal cord. Physiological studies, however, provide additional evidence for direct monosynaptic connections to motoneurons subserving distal musculature. This electron microscopic study demonstrates, by analyzing the anterograde transport of 5% wheatgerm agglutinin-horseradish peroxidase injected into the red nucleus, the presence of labeled terminals synapsing upon somata and proximal dendrites of motoneurons in the lateral portion of the ventral horn of the cervical enlargement of the spinal cord. We conclude that this anatomical evidence confirms the presence of direct monosynaptic connections to spinal motoneurons in the primate. |
Authors:
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D D Ralston; A M Milroy; G Holstege |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Neuroscience letters Volume: 95 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 1988 Dec |
Date Detail:
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Created Date: 1989-03-29 Completed Date: 1989-03-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 102-6 Citation Subset: IM |
Affiliation:
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Department of Anatomy, University of California, San Francisco 94143. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Efferent Pathways / anatomy & histology, physiology Horseradish Peroxidase / diagnostic use Macaca / anatomy & histology* Macaca mulatta / anatomy & histology* Microscopy, Electron Motor Neurons / physiology, ultrastructure* Red Nucleus / anatomy & histology*, physiology, ultrastructure Reflex, Monosynaptic* Spinal Cord / anatomy & histology*, physiology, ultrastructure Synapses / ultrastructure* Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate Wheat Germ Agglutinins / diagnostic use |
| Grant Support | |
ID/Acronym/Agency:
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NS 23347/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; 0/Wheat Germ Agglutinins; EC 1.11.1.-/Horseradish Peroxidase |
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