Document Detail


Ultrastructural and cytochemical studies on nucleolus-like bodies in early postimplantation rat embryos.
MedLine Citation:
PMID:  6181892     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fibrillar cytoplasmic bodies, generally referred to as nucleolus-like bodies (NLBs), have been observed in the embryonic ectodermal cells of early postimplantation rat embryos. The NLBs are not delineated by a membrane, and consist of 5-7 nm filaments. The diameter of the NLBs varies widely, but 0.7-1.2 micrometer is common. Small NLBs are frequently present in the vicinity of the nucleus, suggesting that the filamentous elements of the NLBs may originate from there, and also that these filaments may gradually gather and grow into the NLBs in the cytoplasm. Enzymatic treatment of ultrathin sections obtained from glycol methacrylate-embedded material reveal that a large part of NLBs is removed by digestion with pepsin or pronase, but that various fibrous materials remaining are sensitive to RNase digestion and stained with Bernhard's uranyl-EDTA method. These findings indicate that the NLBs consist of ribonucleoprotein.
Authors:
I K Takeuchi; Y K Takeuchi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell and tissue research     Volume:  226     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-18     Completed Date:  1982-12-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  257-66     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cytoplasmic Granules / physiology,  ultrastructure*
Ectoderm / ultrastructure*
Embryo, Mammalian
Female
Histocytochemistry
Nucleic Acids / analysis
Pregnancy
Rats
Rats, Inbred Strains
Staining and Labeling
Chemical
Reg. No./Substance:
0/Nucleic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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