Document Detail


Ultrastructural characteristics of cells in human wound collected by Cellstic device.
MedLine Citation:
PMID:  6656239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The differentiating human wound cells and intercellular matrix was studied by electron microscopy. The cells were collected with a special wound drain containing a piece of cellulose sponge. Although fibroblastic cells could be detected as early as 20 hr after operation, the main cell population consisted of inflammatory cells. The fibroblastic cells were classified into three types according to the stage of ultrastructural differentiation. Some cells of different types were in close contact by membrane apposition to each other and to the sponge material. However, no specialized junctions were seen. Organized collagen fibers were not seen during the observation period despite the well developed organelles for protein synthesis in the fibroblastic cells. The close contacts of normal cells with the sponge pore walls indicated good compatibility with human tissue and safe use for clinical experiments in routine operations.
Authors:
H J Aho; J Viljanto; J Raekallio; L J Pelliniemi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of surgical research     Volume:  35     ISSN:  0022-4804     ISO Abbreviation:  J. Surg. Res.     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  498-506     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Cell Differentiation
Child
Child, Preschool
Drainage / instrumentation*
Female
Fibroblasts / ultrastructure
Humans
Infant
Infant, Newborn
Leukocytes / ultrastructure*
Lymphocytes / ultrastructure
Macrophages / ultrastructure
Male
Microscopy, Electron
Monocytes / ultrastructure
Neutrophils / ultrastructure
Surgical Procedures, Operative
Wounds and Injuries / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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