Document Detail


Ultrastructural changes in neonatal liver tissue: effects of maternal drinking.
MedLine Citation:
PMID:  6724349     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is already sufficient evidence in the literature that alcohol abuse during pregnancy has a toxic effect upon the developing fetus; however, previous studies have not revealed any morphological changes in fetal or newborn liver specimens from animals exposed to alcohol in utero. As it is known that alcohol freely crosses the placental barrier, this investigation was an attempt to demonstrate that structural abnormalities can indeed be identified in neonatal mouse liver specimens from pups exposed to alcohol in utero. Chosen as a model for this study was the C57BL/KsJ mouse strain as this particular animal demonstrates an alcohol preference paralleling that of the human alcoholic. Findings appear to indicate the presence of abnormal changes on the morphological level in these study animals.
Authors:
K S Amankwah; R C Kaufmann; A D Weberg
Related Documents :
20869959 - Changes in transferrin glycosylation during pregnancy may lead to false-positive carboh...
7026219 - Epidemiological appraisal of the literature on the fetal alcohol syndrome in humans.
9684559 - The biopersistence and pathogenicity of man-made vitreous fibres after short- and long-...
12056499 - Fetal alcohol syndrome--alaska, arizona, colorado, and new york, 1995-1997.
17428259 - Association of maternal fat and alcohol intake with maternal and umbilical hormone leve...
12019589 - Female fertility in relation to the consumption of fish contaminated with persistent or...
7527409 - The phosphorylation pattern of insulin-like growth factor-binding protein-1 in normal p...
19923849 - Successful management of anti-jra alloimmunization in pregnancy: a case report.
18353729 - Radiological treatment of symptomatic uterine fibroids.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  17     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1984  
Date Detail:
Created Date:  1984-07-05     Completed Date:  1984-07-05     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  213-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Newborn
Ethanol / toxicity*
Female
Liver / drug effects,  ultrastructure*
Male
Maternal-Fetal Exchange*
Mice
Mice, Inbred C57BL
Microscopy, Electron
Pregnancy
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Breast engorgement and galactorrhea after preventing premature contractions with ritodrine.
Next Document:  Effect of erythropoietin on acetylation and phosphorylation of bone marrow histones.