Document Detail

Ultrastructural changes of epidermal Langerhans cells in pregnant guinea pigs. A preliminary report.
MedLine Citation:
PMID:  8036869     Owner:  NLM     Status:  MEDLINE    
An association between pregnancy and a depression in cellular immunity has long been known, but the reason for this is far from clear. To investigate the possible role of Langerhans cells (LC) in immunosuppression during pregnancy, we examined the epidermal LC morphology of pregnant guinea pigs ultrastructurally. An altered morphology of epidermal LCs was observed in all specimens obtained from pregnant guinea pigs. LCs were found to be activated in pregnancy.
H Alp; B Durgun; S Müftüoğlu; S Inan; E Aşan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anatomica     Volume:  149     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1994  
Date Detail:
Created Date:  1994-08-16     Completed Date:  1994-08-16     Revised Date:  2007-07-02    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  100-3     Citation Subset:  IM    
Department of Histology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
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MeSH Terms
Epidermis / cytology*
Guinea Pigs
Langerhans Cells / ultrastructure*
Microscopy, Electron
Pregnancy, Animal / physiology*

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