Document Detail

Ultrastructural analysis of the liver with portal vein agenesis: a case report.
MedLine Citation:
PMID:  9891927     Owner:  NLM     Status:  MEDLINE    
Congenital absence of portal vein (CAPV) is a rare vascular malformation: all 16 cases up to now reported are associated with other congenital anomalies and with benign or malignant hepatic neoplasms. Our report concerns a girl with a complex malformative syndrome consisting of CAPV, nodular tumor-like hyperplasia of the liver, and multicystic kidney dysplasia. CAPV was diagnosed by angiography, showing the splenic vein and superior mesenteric vein joined to form a "common trunk" directly entering the inferior vena cava above the liver. The liver maintained the normal lobular architecture, but immunohistochemical and ultrastructural observations revealed abnormalities of the hepatocyte membranes and diffuse capillarization of the sinusoids. In this paper, we present the relationship between the tissue modification and the lobular microcirculation changes due to CAPV, with exclusive perfusion of arterial blood flow.
G Altavilla; P Cusatelli
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ultrastructural pathology     Volume:  22     ISSN:  0191-3123     ISO Abbreviation:  Ultrastruct Pathol     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  1999-03-18     Completed Date:  1999-03-18     Revised Date:  2009-06-26    
Medline Journal Info:
Nlm Unique ID:  8002867     Medline TA:  Ultrastruct Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  477-83     Citation Subset:  IM    
Istituto di Anatomia Patologica, Universita degli Studi di Padova.
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MeSH Terms
Abnormalities, Multiple / pathology*
Immunoenzyme Techniques
Kidney / abnormalities
Liver / blood supply*,  chemistry,  ultrastructure*
Polycystic Kidney Diseases / congenital
Portal Vein / abnormalities*,  ultrastructure
Regional Blood Flow
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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