Document Detail

Ultrasound-promoted synthesis of novel dispirocyclic frameworks from aza-Claisen rearrangements of Baylis-Hillman amines.
MedLine Citation:
PMID:  18848799     Owner:  NLM     Status:  MEDLINE    
A novel tetracyclic frameworks of dispiropyrrolizidines can be obtained in moderate to good yields via the 1,3-dipolar cycloaddition of azomethine ylides with dipolarophiles derived from aza-Claisen rearrangement of Baylis-Hillman amines. The transformations are highly regioselective and stereoselective, affording the desired compounds in reduced time and increased yields under ultrasound irradiation at room temperature. All the products are confirmed by 1H, 13C NMR, IR and MS spectra, while their molecular structures are elucidated by X-ray crystallography of a selected sample.
Shao-Qin Ge; Yun-Yu Hua; Min Xia
Related Documents :
12375949 - Uncatalyzed [4 + 2] cycloadditions of 3-nitrocoumarins with vinyl ethers in solventless...
24109349 - Bis(2,4,6-tri-amino-pyrimidin-1-ium) sulfate penta-hydrate.
22909419 - Design strategies for shape-persistent covalent organic polyhedrons (cops) through imin...
22397549 - Delocalization-to-localization charge transition in diferrocenyl-oligothienylene-vinyle...
25263889 - Synthesis and application of polypyrrole/carrageenan nano-bio composite as a cathode ca...
22823519 - Exploring the potential of doped zero-dimensional cages for proton transfer in fuel cel...
24299029 - Acceptorless dehydrogenation of c-c single bonds adjacent to functional groups by metal...
20711859 - Heavy metal concentrations in some macrobenthic fauna of the sundarbans mangrove forest...
17523799 - Infrared spectroscopy of cu+(h2o)(n) and ag+(h2o)(n): coordination and solvation of nob...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-11
Journal Detail:
Title:  Ultrasonics sonochemistry     Volume:  16     ISSN:  1350-4177     ISO Abbreviation:  Ultrason Sonochem     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-10-30     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433356     Medline TA:  Ultrason Sonochem     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  232-6     Citation Subset:  IM    
Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, P.R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amines / chemistry*,  radiation effects*
Aza Compounds / chemistry*,  radiation effects*
Indicators and Reagents
Isatin / chemistry
Models, Molecular
Proline / chemistry
Pyrrolizidine Alkaloids / chemical synthesis*,  radiation effects
Spiro Compounds / chemical synthesis*,  radiation effects
X-Ray Diffraction
Reg. No./Substance:
0/Amines; 0/Aza Compounds; 0/Indicators and Reagents; 0/Pyrrolizidine Alkaloids; 0/Spiro Compounds; 147-85-3/Proline; 91-56-5/Isatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pyomyositis caused by extended-spectrum beta-lactamase-producing Escherichia coli in a patient with ...
Next Document:  Kinetics of the ultrasonic degradation of poly (alkyl methacrylates).