Document Detail

Ultrasound prediction of fetal lung maturity.
MedLine Citation:
PMID:  3885311     Owner:  NLM     Status:  MEDLINE    
Amniocentesis for determination of fetal lung maturity and ultrasonographic (US) evaluation of the biparietal diameter (BPD) and placental grade were performed simultaneously in 261 nondiabetic pregnant women. A BPD of at least 9.3 cm and a grade 3 placenta were evaluated as predictors of fetal lung maturity using amniotic fluid phospholipids as indicators of a mature lung profile. The ability of the sonographic parameters to predict fetal lung maturity was closely related to menstrual age. Before 37 weeks, the false-positive prediction rate using a grade 3 placenta was 100%, and the false-positive prediction using the BPD was 85.6%. After 37 weeks, the false-positive rate using a grade 3 placenta was 5.9%, and the false-positive rate using the BPD was 9.5%. Thus menstrual age, and not these two US parameters, dictated fetal lung maturity. The authors conclude that the best use of US for predicting fetal lung maturity is in establishing menstrual age early in pregnancy.
F P Hadlock; J F Irwin; E Roecker; Y P Shah; R L Deter; I K Rossavik
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  155     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-05-14     Completed Date:  1985-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  469-72     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis
False Positive Reactions
Fetal Organ Maturity*
Fetus / anatomy & histology
Gestational Age
Lung / embryology*
Phosphatidylglycerols / analysis
Placenta / anatomy & histology
Reg. No./Substance:

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