| Ultrasound measurement of skin thickness in systemic sclerosis. | |
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MedLine Citation:
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PMID: 7633795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sclerotic skin change in systemic sclerosis (SSc) usually accompanies increased skin thickness. In order to quantify the cutaneous changes and to clarify the changes in the 'uninvolved' skin in systemic sclerosis (SSc), we measured the skin thickness on the chest, the forearms and the hands of 79 patients with SSc and 81 healthy controls with a B-mode ultrasound (30 MHz) apparatus. The thickness of the 'uninvolved', as well as the 'involved' skin in patients with SSc was significantly greater than that of healthy controls. Increased skin thickness on the forearms and/or the hands showed a 64.6% sensitivity and a 100% specificity for SSc. These results indicated that the skin which appears to be 'uninvolved' in patients with SSc is already pathologic, as shown by increased thickness. Moreover, measurement of skin thickness may be beneficial in the diagnosis of this disease at an early stage. |
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Authors:
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H Ihn; M Shimozuma; M Fujimoto; S Sato; K Kikuchi; A Igarashi; Y Soma; K Tamaki; K Takehara |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of rheumatology Volume: 34 ISSN: 0263-7103 ISO Abbreviation: Br. J. Rheumatol. Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-09-13 Completed Date: 1995-09-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302415 Medline TA: Br J Rheumatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 535-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Female Forearm Hand Humans Male Middle Aged Scleroderma, Systemic / ultrasonography* Skin / ultrasonography* Thorax |
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