Document Detail

Ultrasound-guided transversus abdominis plane block in children: a randomised comparison with wound infiltration.
MedLine Citation:
PMID:  23338056     Owner:  NLM     Status:  MEDLINE    
CONTEXT: The transversus abdominis plane (TAP) block is a new regional anaesthesia technique applicable to infants and children.
OBJECTIVE(S): The present study was designed to evaluate the analgesic efficacy of ultrasound-guided TAP block with high volume local anaesthetic (0.5  ml kg) during the first 24 h after surgery in children undergoing inguinal hernia repair.
DESIGN: Randomised comparative study.
SETTING: Gaziantep University Hospital between December 2010 and May 2011.
PATIENTS OR OTHER PARTICIPANTS: Fifty-seven children between 2 and 8 years of age undergoing unilateral inguinal hernia repair were randomised to TAP block (group T, n = 29) or to wound infiltration (group C, n = 28).
INTERVENTION(S): A TAP block using ultrasound guidance with 0.25% levobupivacaine 0.5  ml kg(-1) or wound infiltration with 0.2  ml kg(-1) 0.25% levobupivacaine, was performed on the same side as the hernia under general anaesthesia.
MAIN OUTCOME MEASURES: Time to first analgesic, cumulative number of doses of analgesic, pain scores and adverse effects were assessed over the course of 24  h.
RESULTS: The time to first analgesic (mean ± SD) was significantly longer in group T than in group C (17 ± 6.8 vs. 4.7 ± 1.6 h, respectively; P < 0.001). Thirteen (45%) patients in group T did not require any analgesic within the first 24 h. The cumulative number of doses of analgesic was significantly lower in group T than in group C (1.3 ± 1.2 vs. 3.6 ± 0.7, respectively, P < 0.001). Pain scores were significantly different between the groups at all time points except at 1, 20 and 24  h (P < 0.001).
CONCLUSION: Ultrasound-guided TAP block with high volume (0.5 ml kg) 0.25% levobupivacaine provides prolonged postoperative analgesia and reduced analgesic use without any clinical side-effects after unilateral hernia repair in children.
TRIAL REGISTRATION: ACTRN12611000585921 (7/06/2011) from Australian New Zealand Clinical Trials Registry.
Levent Sahin; Mehrican Sahin; Rauf Gul; Vahap Saricicek; Nurgul Isikay
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  30     ISSN:  1365-2346     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-07     Completed Date:  2013-11-18     Revised Date:  2014-01-13    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  409-14     Citation Subset:  IM    
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MeSH Terms
Abdominal Muscles / pathology*
Analgesics / therapeutic use
Anesthesia, Conduction / methods*
Anesthetics / therapeutic use
Child, Preschool
Hernia, Inguinal / surgery
Nerve Block / methods
Pain, Postoperative / therapy
Time Factors
Ultrasonography / methods*
Wounds and Injuries / drug therapy,  pathology*
Reg. No./Substance:
0/Analgesics; 0/Anesthetics
Comment In:
Eur J Anaesthesiol. 2014 Jan;31(1):60   [PMID:  24145808 ]
Eur J Anaesthesiol. 2014 Jan;31(1):59   [PMID:  24145809 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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