Document Detail

Ultrasound-guided injection of ectopic pregnancy.
MedLine Citation:
PMID:  10073298     Owner:  NLM     Status:  MEDLINE    
Preliminary studies have demonstrated that salpingocentesis is a safe and effective treatment for unruptured ectopic pregnancies that are visible by transvaginal ultrasound. So far, experience with this technique has been confined to only a few centers around the world. The most promising results of these studies has been the virtual absence of side effects associated with local injection of either methotrexate or hyperosmolar glucose. Large prospective trials comparing efficacy, safety, and overall cost of salpingocentesis against systemic methotrexate will be necessary to better define the role of salpingocentesis in the management of ectopic pregnancy. Patient recruitment for this type of clinical trial would be feasible and acceptable to patients because both treatment arms would avoid surgery.
J G Natofsky; J Lense; J C Mayer; T R Yeko
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  42     ISSN:  0009-9201     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-29     Completed Date:  1999-04-29     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-47; quiz 55-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa 33606, USA.
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MeSH Terms
Folic Acid Antagonists / administration & dosage,  therapeutic use
Methotrexate / administration & dosage,  therapeutic use
Pregnancy, Ectopic / drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Folic Acid Antagonists; 59-05-2/Methotrexate

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