Document Detail

Ultrasound-guided embryo transfer maximizes the IVF results on day 3 and day 4 embryo transfer but has no impact on day 5.
MedLine Citation:
PMID:  11527896     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The use of ultrasound-guided embryo transfer has been reported to affect success rates in some centres but not others. In a prospective study, we examined the influence of ultrasound guidance in embryo transfer performed on different days after oocyte retrieval. METHODS: Two different methods of embryo transfer were evaluated in 1069 consecutive transfers. The ultrasound-guided embryo transfer was used in 433 cases, whereas 636 embryo transfers were performed with the tactile assessment ('clinical feel') method. RESULTS: Ultrasound-guided embryo transfer yielded a higher overall pregnancy rate than the 'clinical feel' approach, 47 versus 36% (P < 0.001). This difference was statistically significant where embryos were transferred after 3 or 4 days of culture, 45.9 versus 37.1% (P = 0.001) and 42.3 versus 27% (P = 0.035) respectively but not significant (P = 0.112) on day 5 embryo transfer (56.3 versus 45.7%). Likewise, the implantation rate was significantly different between the two groups on day 3 and 4 embryo transfer, 23.3 versus 15.8% (P < 0.01) and 21.6 versus 15.7% (P < 0.05%) respectively but no statistical difference was noted on day 5 embryo transfer, 26.7 versus 23.6%. CONCLUSION: Ultrasound assistance in embryo transfer on day 3 and 4 significantly improved pregnancy rates in IVF but had no impact on day 5.
Y Prapas; N Prapas; A Hatziparasidou; P Vanderzwalmen; M Nijs; S Prapa; G Vlassis
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  16     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-08-30     Completed Date:  2001-12-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  1904-8     Citation Subset:  IM    
4th Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloniki Greece.
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MeSH Terms
Culture Techniques
Embryo Implantation
Embryo Transfer / standards*
Pregnancy Rate*
Prospective Studies
Time Factors
Comment In:
Hum Reprod. 2002 Apr;17(4):1131; author reply 1132   [PMID:  11925424 ]
Hum Reprod. 2002 Apr;17(4):1129-30; author reply 1130-1   [PMID:  11925421 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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