| Ultrasound-enhanced transdermal transport. | |
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MedLine Citation:
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PMID: 12761802 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The enhancement of transdermal transport by ultrasound is reviewed. After a brief discussion of the physics of ultrasound and its medical applications, the effects of high- and low-frequency ultrasound on the transport of substances across the skin are examined. The impact of low-frequency sonophoresis appears to be much more important, with significant increases in transport into and from the skin following its application. Although the mechanism of action remains incompletely defined, cavitation and thermal processes are strongly implicated. |
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Authors:
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Gustavo Merino; Yogeshvar N Kalia; Richard H Guy |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of pharmaceutical sciences Volume: 92 ISSN: 0022-3549 ISO Abbreviation: J Pharm Sci Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-05-22 Completed Date: 2004-01-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985195R Medline TA: J Pharm Sci Country: United States |
Other Details:
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Languages: eng Pagination: 1125-37 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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School of Pharmacy, Faculty of Sciences, University of Geneva, 30 quai E-Ansermet, CH-1211 Geneva 4, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Animals Biological Transport Chemistry, Pharmaceutical Humans Pharmaceutical Preparations / administration & dosage* Pharmacokinetics Skin / metabolism* Skin Absorption Ultrasonics* |
| Chemical | |
Reg. No./Substance:
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0/Pharmaceutical Preparations |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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