| Ultrasound-enhanced Thrombolysis. | |
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MedLine Citation:
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PMID: 17484537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report a single-center clinical experience with ultrasound-enhanced thrombolysis in the treatment of both arterial and venous thromboses. METHODS: From January 2005 to June 2006, 33 patients (23 men; age range 39-90 years) with 36 occlusions were treated using ultrasound-enhanced thrombolytic therapy for acute and chronic arterial and venous occlusions. After diagnostic angiography, the occlusions were crossed with an appropriately sized Lysus infusion catheter for infusion of urokinase (80,000-120,000 IU/h). RESULTS: Technical success and complete lysis was achieved in 96% of the arterial and 83% of the venous occlusions. Two patients with chronic occlusions (one superficial femoral artery and one iliac vein) were refractory to lytic therapy. Average time for complete lysis was 16.4 hours (range 3-25) for arterial occlusions and 21.2 hours (range 6-43) in patients with deep vein thrombosis. CONCLUSION: Successful clot lysis can be achieved with a high rate of success in a shorter time than conventional thrombolysis using ultrasound-enhanced thrombolysis in both acute and chronic arterial and venous thromboses. |
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Authors:
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Amir Motarjeme |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists Volume: 14 ISSN: 1526-6028 ISO Abbreviation: J. Endovasc. Ther. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-05-08 Completed Date: 2007-07-05 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100896915 Medline TA: J Endovasc Ther Country: United States |
Other Details:
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Languages: eng Pagination: 251-6 Citation Subset: IM |
Affiliation:
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Midwest Vascular Institute of Illinois, Downers Grove, Illinois 60515, USA. Midwestvascular@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Aged, 80 and over Arterial Occlusive Diseases / drug therapy, physiopathology, radiography, therapy* Chronic Disease Combined Modality Therapy Female Fibrinolytic Agents / therapeutic use* Follow-Up Studies Humans Male Middle Aged Radiography, Interventional Recurrence Thrombolytic Therapy* / instrumentation Thrombosis / drug therapy, physiopathology, radiography, therapy* Time Factors Treatment Outcome Ultrasonic Therapy* / instrumentation Urokinase-Type Plasminogen Activator / therapeutic use* Vascular Patency Venous Thrombosis / drug therapy, therapy |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.21.73/Urokinase-Type Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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