Document Detail

Ultrasound determined carotid and femoral atherosclerosis in Lithuanian and Swedish men: the LiVicordia study.
MedLine Citation:
PMID:  10924727     Owner:  NLM     Status:  MEDLINE    
Coronary heart disease mortality is four times higher in Lithuanian compared to Swedish middle-aged men. Using the same equipment (Acuson XP10 with 5 MHz linear transducer) and staff, we compared the amount of atherosclerosis in carotid and femoral arteries in 100 randomly sampled 50-year-old men in each of the cities Vilnius, Lithuania and Linköping, Sweden. Atherosclerotic plaques were more abundant in Vilnius men compared to Linköping men (53 versus 28% in the common carotid artery, 73 versus 37% in the common femoral artery, P < 0.001 for both). Plaques were thicker and more extended in arteries of Vilnius men, and an ultrasound atherosclerosis score was higher in both carotid and femoral arteries (P < 0.001 for all). More Vilnius men had a maximal intima-media thickness of the common femoral artery above 1 mm (P<0.005). Stiffness in the common carotid artery was higher in Vilnius men (P<0.001). In a linear regression model of the pooled material, after adjustment for city was made, smoking, systolic blood pressure, low density lipoprotein cholesterol and beta-carotene (inversely) significantly contributed to a high total ultrasound score (r2 = 0.32). These findings show that the higher coronary mortality noted in Lithuanian men goes together with a higher prevalence of early peripheral atherosclerosis.
M Kristenson; C Lassvik; B Bergdahl; Z Kucinskiène; L Aizieniène; Z Bo; L S Elinder; A G Olsson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Atherosclerosis     Volume:  151     ISSN:  0021-9150     ISO Abbreviation:  Atherosclerosis     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-11-13     Completed Date:  2000-11-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  501-8     Citation Subset:  IM    
Department of Health and Environment, Faculty of Health Sciences, Linköping, Sweden.
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MeSH Terms
Arteriosclerosis / etiology,  physiopathology,  ultrasonography*
Carotid Arteries / physiopathology,  ultrasonography
Carotid Artery Diseases / etiology,  physiopathology,  ultrasonography*
Cross-Sectional Studies
Femoral Artery / physiopathology,  ultrasonography*
Middle Aged
Risk Factors
Tunica Intima / ultrasonography
Tunica Media / ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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