| Ultrasound determined carotid and femoral atherosclerosis in Lithuanian and Swedish men: the LiVicordia study. | |
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MedLine Citation:
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PMID: 10924727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Coronary heart disease mortality is four times higher in Lithuanian compared to Swedish middle-aged men. Using the same equipment (Acuson XP10 with 5 MHz linear transducer) and staff, we compared the amount of atherosclerosis in carotid and femoral arteries in 100 randomly sampled 50-year-old men in each of the cities Vilnius, Lithuania and Linköping, Sweden. Atherosclerotic plaques were more abundant in Vilnius men compared to Linköping men (53 versus 28% in the common carotid artery, 73 versus 37% in the common femoral artery, P < 0.001 for both). Plaques were thicker and more extended in arteries of Vilnius men, and an ultrasound atherosclerosis score was higher in both carotid and femoral arteries (P < 0.001 for all). More Vilnius men had a maximal intima-media thickness of the common femoral artery above 1 mm (P<0.005). Stiffness in the common carotid artery was higher in Vilnius men (P<0.001). In a linear regression model of the pooled material, after adjustment for city was made, smoking, systolic blood pressure, low density lipoprotein cholesterol and beta-carotene (inversely) significantly contributed to a high total ultrasound score (r2 = 0.32). These findings show that the higher coronary mortality noted in Lithuanian men goes together with a higher prevalence of early peripheral atherosclerosis. |
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Authors:
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M Kristenson; C Lassvik; B Bergdahl; Z Kucinskiène; L Aizieniène; Z Bo; L S Elinder; A G Olsson |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Atherosclerosis Volume: 151 ISSN: 0021-9150 ISO Abbreviation: Atherosclerosis Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-11-13 Completed Date: 2000-11-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: IRELAND |
Other Details:
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Languages: eng Pagination: 501-8 Citation Subset: IM |
Affiliation:
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Department of Health and Environment, Faculty of Health Sciences, Linköping, Sweden. margareta.kristenson@lio.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arteriosclerosis
/
etiology,
physiopathology,
ultrasonography* Carotid Arteries / physiopathology, ultrasonography Carotid Artery Diseases / etiology, physiopathology, ultrasonography* Cross-Sectional Studies Elasticity Femoral Artery / physiopathology, ultrasonography* Humans Lithuania Male Middle Aged Risk Factors Sweden Tunica Intima / ultrasonography Tunica Media / ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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